Biotech Cancer Conference Coverage

Commentary on Science, Innovation & New Products

How Syros are changing biotech R&D

We have written about small biotechs and big pharma a lot on this blog, particularly when they have exciting new developments in their pipeline to review and consider.  Increasingly, we have also begun to look at the early phase companies because often, that is where some fresh ideas and approaches are being developed and tested.

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Will Bluebird Bio transform beta Thalassemia and Sickle Cell Anemia?

Beta thalassemia isn’t something you read much about in the medical lay press, at least until recently.  Part of the problem is the lack of approved therapies, as well as the dearth of new products being evaluated in this condition.  It’s also more common in the Mediterranean, Middle East and Asia compared to the US, where it’s medical cousin, sickle cell anemia, dominates.

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Biomarin PARP inhibitor talazoparib shows promise in gBRCA Breast Cancer

The DNA in a human cell undergoes thousands damaging events per day, generated by both external (exogenous) and internal metabolic (endogenous) processes. Unfortunately, some of these changes can generate errors in the transcription of DNA and subsequent translation into proteins necessary for signaling and cellular function. Genomic mutations can also be carried over into future generations of cells, if the mutation is not repaired prior to mitosis.

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