Biotech Strategy Blog

Commentary on Science, Innovation & New Products with a focus on Oncology, Hematology & Cancer Immunotherapy

Posts tagged ‘neon therapeutics’

At the recent scientific meeting to celebrate the 40th anniversary of the Centre d’Immunologie de Marseille-Luminy (#CIML40), Professor Ton Schumacher from the Netherlands Cancer Institute gave an informative presentation on “T cell recognition and tumor resistance in human cancer.”

Professor Ton Schumacher at CIML40

Picture Credit: ATGC Partners

Schumacher started his talk at CIML by saying, “I guess by now I should consider myself a cancer immunologist…”

Cancer immunologist ‘wannabes’ should take note of the level of expertise required to be considered one!

Neon Therapeutics LogoHe is one of the co-founders of Neon Therapeutics and a leading researcher into antigen-specific T cell immunity.

Several companies are seeking to develop personalized cancer vaccines against patient-specific neoantigens.

We previously wrote about the approach Neon Therapeutics is following based on expert interviews with the interim CEO Cary Pfeffer and scientific co-founder Dr Cathy Wu.

BioNTech LogoYesterday the field heated up when it was announced that German biotech BioNTech AG had entered a strategic collaboration with Genentech to develop individualized mRNA cancer therapies (Sept 20, 2016 press release).

This post continues the BSB mini-series on targeting neoantigens that we started last month. Do check out previous posts if you missed them:

After his #CIML40 presentation, Prof Schumacher kindly spoke to BSB.

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As we continue our journey exploring neoantigens in the context of novel cancer research in Part 3 of our latest mini-series, today we focus on the commercialisation side of the business through an interview with a leading investor, Dr Cary Pfeffer, who is a partner in Third Rock Ventures, as well as being ad interim CEO of Neon Therapeutics.  We’ve written about other Third Rock companies in the past; Agios, Foundation Medicine and bluebird bio come to mind, for example.

neonlogoHow does an exciting early product in development move from academia to industry? There are many ways to do this, so here is the story through the eyes of one young company with strong academic connections, as a way to illustrate what can be done. It isn’t the only way, by any means.

To be sure, there are other competitor companies in the neoantigen space – Gritstone and Moderna come to mind as examples – we will cover companies in the broader landscape in a future post. There is also an incredible amount of promising research going on in academia right now, which may lead to more companies or products being licensed and developed.

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