New Orleans – one of the presentations of note at Immunology 2015 (the annual meeting of the American Association of Immunologists) was by Thomas J. Gajewski MD, PhD from the University of Chicago. His presentation on “Innate immune sensing of cancer via the STING pathway” was well worth the trip to New Orleans.
Readers may recall the post we wrote in March on “What is STING and why does it matter in cancer immunotherapy?” It followed the news that Novartis were collaborating with Aduro Biotech (NASDAQ: ADRO) on agonists that activate the STING (Stimulator of Interferon Genes) signaling pathway in immune cells.
Dr Gajewski (pictured below) kindly spoke to BSB after his presentation at Immunology 2015.
You should read and/or buy access to this post if you don’t know the answers to the following:
- What role does the tumor microenvironment play in response to cancer immunotherapy?
- How could the tumor microenvironment be a biomarker of response to checkpoint inhibitors?
- Why target the STING pathway?
- Reasons Novartis are collaborating with Aduro Biotech?
- How may a STING agonist be brought to the clinic?