Biotech Strategy Blog

Commentary on Science, Innovation & New Products with a focus on Oncology, Hematology & Cancer Immunotherapy

Posts tagged ‘Adoptive T cell therapy’

If the best way to predict the future is to invent it then the poster sessions at the AACR annual meeting are frequently a window into the next generation of cancer drugs and therapies. Regular attendees at AACR will know that there are gems to be found in the posters, and that preclinical research on display may end up being translated into the clinic not long afterwards.

Like wearing a new set of clothes for lunch and dinner, with the exception of the first and last days, there’s a different set of posters in the morning and afternoon – that’s a lot of posters one can get through during a conference!

Indeed, MSKCC Chief Analytics Officer, Ari Caroline, noted on Twitter, “I may have spent more time at AACR this year at the posters than at the sessions.”

Dr Larry Lamb CSO Incysus

One story that we continue to follow this year is the emerging interest in unconventional T cells. The good news was that there was new data at AACR19.

We covered Puretech Health and their posters last week while another related one in the same niche that caught our attention was presented by Dr Lawrence Lamb (right).

On April 1, 2019 Incysus announced that the FDA had approved their IND application for a novel gamma-delta T cell therapy for treatment of patients with newly diagnosed glioblastoma (link to press release).

At AACR19 we met up with Dr Lamb, who is now Chief Scientific Officer of Incysus Therapeutics, to find out more about his research and how Incysus plan to translate it into the clinic.

This is a continuation of our series on gamma delta (𝞬𝝳) T cells exploring the multitude of different ways that illustrate their potential for cancer immunotherapy in hematologic malignancies and solid tumours.

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One of my favourite meetings of the year in our conference calendar is the American Association for Cancer Research (AACR) annual meeting, which is held in the spring. In years past, the agenda at this event has set the scene for the rest of the year in terms of emerging new trends, particularly with regards to targeted therapies. In the last two years though, this hasn’t been the case, as adjusting to the brave new world of immunotherapies has taken some time.

The good news is that AACR has come roaring back in 2015 with a star-studded line-up that includes some of the big hitters and sluggers in the cancer immunology space.

What’s in store for this year, you may well be wondering, and where are we likely to see the new trends evolve?

We took an in-depth look at what’s hot in immunotherapies and where the new directions are going in this latest conference preview, the first one in series relating to the AACR annual meeting being held in Philadelphia from April 18–22nd (Twitter #AACR15).

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