Biotech Strategy Blog

Commentary on Science, Innovation & New Products with a focus on Oncology, Hematology & Cancer Immunotherapy

Posts tagged ‘CRISPR screens’

This is the penultimate post in our mini-series looking at the potential of immunometabolism for cancer new product development. The initial plans for six posts ended up being revised with a seventh and final article based on an additional thought leader interview.

What’s the immunometabolism prize?

Like a series of postcards from our travels, the aim was to offer a flavor of different approaches in the field, some of which are already being translated and evaluated by biotech companies in clinical trials.

Along the way, like conversations on a journey, we spoke to several scientists working at the forefront of this research. As regular readers know we don’t just interview the ‘great and good’ – the established PI’s but in this series – we also spoke to some emerging up and coming researchers too. Each offered a unique personal perspective on different aspects of metabolism and its potential role in cancer research.

In today’s post, we share an interview with a young researcher working on a novel and intriguing approach, which could improve adoptive cell therapy.

We expect to hear a lot more about many of the immunometabolic strategies we’ve highlighted over the course of coming months, so this is a theme we will return to as new data emerges.

To learn more about the emerging area of immunometabolism and its potential to enhance adoptive cell therapy, subscribers can log-in or you can click to gain access to BSB Premium Content.

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Over the last four or five weeks we have seen some truly remarkable research published by numerous cancer researchers around the globe… which means that it’s time for another Journal Club review of key research to feature some cool science.

Here, we have selected half a dozen key papers of interest in both solid tumours and hematological malignancies that are well worth reading and digesting.  The impact from many of these may well lead to new molecules being explored.  We also include at least one review paper for BSB readers to peruse.

While much of the focus is inevitably on lung cancer and melanoma of late, we also highlight important research in pancreatic cancer, aggressive lymphomas and AML.

To learn more insights on this intriguing topic, subscribers can log-in or you can click to gain access to BSB Premium Content.

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