Making waves with new directions – there are many possible ways to go when considering targeting the adenosine axis
As we segue between our AACR and ASCO coverage, one topic that straddles both virtual meetings is targeting the adenosine axis. At AACR19, this pathway was very much front and square with some intriguing and controversial data presented, which caught many people by surprise.
Since then, several companies have opened new trials, others are completing enrollment and waiting for their data to readout before deciding upon next steps.
It’s a good time to take a look at what’s new in this niche and also see things differently through the lens of one company involved in the field. Yes, it’s time to share our latest expert interview from not one, but two, c-suite executives.
What are their perspectives (they are different), where do they see the field going and why?
In part one of the discussion we focus exclusively on adenosine targeting and how they see themselves differentiated from the crowd… it certainly makes for interesting reading!
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The AACR19 ‘mosh pit’ where gems abound
It’s been a while since we looked at the adenosine pathway, where a fog of immunosuppression is thought to cloak the ability of the immune system to induce antitumour immunity.
When we first wrote about the A2A receptor-CD73-CD39 pathway in 2016 there really weren’t very many players in this niche. Since then the field has expanded quite considerably and there are now more companies and molecules to consider.
As we straddle AACR and ASCO, it’s a great time to offer an update and look at what we learned…
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