E

Beyond the Topo-I Rush: Finding Space in a Crowded ADC Landscape

When the future of ADCs and bispecifics collide

November 11, 2024
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RevMed’s approach to kicking KRAS to the kerb

Challenges and opportunities go hand in hand with early drug development

October 29, 2024
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An unexpected emerging onco landscape to watch out for

Which Thunderbirds are Go in this niche?!

October 22, 2024
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What can aviation teach us about ADCs and bispecific antibodies?

The best marketing cannot solve a major product weakness in your compound

October 10, 2024
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Pointers to consider in SCLC developments

Red and green flags to watch out for in relapsed SCLC

September 8, 2024
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ESMO24 Preview 7 – Lighting Up Early Stage Research

On biomarkers, acquired resistance and immune escape, oh my!

August 29, 2024
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New opportunities for Menin inhibitors

Which combinations make rational sense and which might see action in the clinic?

August 7, 2024
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Sorting out the clunkers in a crowded field

Where is the ADC space heading and waht issues need to be addressed?

July 3, 2024
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Making mountains out of molehills

Early stage oncology new product development is a rather strange beast at times. On the one hand is the…

June 27, 2024
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New directions in a post IO apocalypse

Where to pivot next? That's the question...

June 13, 2024
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Bicycling to new heights

Can bicyclic toxin and radio conjuates do a better job than ADCs and RLTs?

June 11, 2024
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Degraders and glues – time for a pitstop

Who's going to be roaring forward?

June 6, 2024
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A new dawn or the sunsetting of cytokines?

It's time to challenge our thinking on cytokines

May 24, 2024
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Another bite at the cherry

Can a new generation of bispecifics change our mind about a particular target?

May 6, 2024
E

An innovative approach to tackling KRAS

Switching focus in the critical KRAS pocket

May 2, 2024
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Bridging the gap between AACR and ASCO

Segueing between preclinical and clinical data

April 25, 2024
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A smorgasbord of new agents

Next generation agents or a new drug class?

April 23, 2024
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All is not what it seems

In beast mode – or not?

April 18, 2024
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The Eye of the Tiger

Where epigenetics and synthetic lethality converge

April 14, 2024
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Kicking KRAS to the kerb

How protecting both the on and the blindside may delay resistance and improve outcomes

April 11, 2024
E

Lessons learned from AACR24 – Part 1

The AACR annual meeting is an opportunity to challenge established paradigms and scientific dogma. In…

April 9, 2024
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Translating Scientific Insights into Competitive Advantage

How kicking things up a notch by thinking outside the box may pay dividends

April 8, 2024
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How creative thinking can turn our heads

Finding solutions for tough to drug targets

April 7, 2024
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On biomarkers and bispecifics

When the going gets tough, the tough get going...

March 28, 2024
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Cancer’s Tiny Doppelgangers

An emerging research tool to watch out for in oncology new product development

March 25, 2024
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Just can’t get enough

A vertical and horizontal fishing expedition in new product development

March 21, 2024
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Molecular Jiu-Jitsu – Turning Cancer’s Mistakes Against Itself

Our 7th AACR Preview takes stock of an emerging class of anti-cancer agents

March 18, 2024
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A dozen early stage clinical trials to watch out for at AACR24

In 2011 we did an annual ASCO highlight video reel of what to watch out for. Three phase 1…

March 14, 2024
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An unexpected surprise!

In our fifth preview from the AACR annual meeting being held in San Diego next month, we noticed some…

March 12, 2024
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10 things I learned about ADCs at AACR 2024

The good, the bad, and the ugly under belly of the next flurry of ADCs

March 8, 2024
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What happens when an intractable target becomes druggable-ish

W2W4 - what to watch for in an emerging oncology niche

March 5, 2024
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ADCs – Controversies, Challenges, and Opportunities

Finding nuance and solutions amongst the clutter

February 27, 2024
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Dark side of the moon

What happens when multiple oncogenic pathways converge at the crossroads? An important aspect to watch out for heading into AACR24

February 22, 2024