UCL Drives CD19 CAR T Cell Therapy Forward in Europe

University College London (UCL) is leading the way in European clinical trials of CAR T Cell therapies that target CD19.

April 14, 2015

How to enhance checkpoint inhibitors in hematologic malignancies

Will checkpoint inhibitors make an impact in hematologic malignancies or will novel combinations be needed?

March 4, 2015

CAR-T Cell Therapies from China are a Competitive Threat

Cellular Biomedicine Group (NASDAQ: CBMG) has acquired rights to the Chimeric Antigen Receptor T cell (CAR-T) therapy of the PLA General Hospital in Beijing.

February 11, 2015

The application of TILs, CARs and TCRs in cancer research

What does the evolving landscape for CAR, TIL and TCR cell therapies look like?

February 10, 2015

Tumour infiltrating lymphocytes TILs: what are they and why do they matter?

The NCI have been at the forefront of developing novel cancer immunotherapies for several decades, but what is the current status of their groundbreaking work? Find out more in this primer on TILs.

February 5, 2015

Will venetoclax impact in hematologic malignancies

ABT-199 is now known as venetoclax - has it overcome it's checkered history to get back on track?

February 4, 2015

bluebird bio CEO Nick Leschly seeks to make hope a reality

Bluebird bio is an emerging biotech company with a novel lentiglobin gene therapy in development that could revolutionize the treatment of beta-thalassemia and sickle cell disease.

January 14, 2015

Will Bluebird Bio transform beta Thalassemia and Sickle Cell Anemia?

There is no available cure for patients with beta-thalassemia or sickle cell disease, but new developments are very encouraging

January 12, 2015

Cellectis ramps up CAR-T development in 2015

What makes the Cellectis Chimeric Antigen Receptor CAR-T cell therapy different and what are the milestones expected in 2015?

January 6, 2015

Targeting the unmet medical need in GvHD

Graft versus Host disease (GvHD) is an area of tremendous unmet medical need that is triggering the interest of a number of biotech and rare disease companies.

January 5, 2015

ASH 2014 Day 3 Live blog #ASH14

"Manic Monday" at the annual meeting of the American Society of Hematology features multiple oral sessions run at the same time!

December 8, 2014

ASH 2014 Day 2 Live Blog #ASH14

Coverage of Day 2 of the annual meeting of the American Society of Hematology in San Francisco.

December 7, 2014

ASH 2014 Day 1 Live Blog #ASH14

It's Day 1 of the 2014 annual meeting of the American Society of Hematology meeting in San Francisco.

December 6, 2014

Top 10 AML abstracts at ASH 2014

There are a lot of new products in development for AML. Here's my top 10 abstracts to watch out for at ASH 2014 in San Francisco.

December 4, 2014

ASH 2014 Hodgkins Lymphoma and DLBCL Preview

Preview of ASH 2014 Key Abstracts in Lymphomas including HL and aggressive DLBCL

December 3, 2014

ASH 2014 Annual Meeting Multiple Myeloma Preview

ASH 2014 Multiple Myeloma data looks like it offers much promise for new treatments as well as an increasingly competitive marketplace

December 2, 2014

Agios IDH1 Inhibitor AG-120 shows promise in AML $AGIO

Agios AG-120 IDH1 Inhibitor shows promise in acute myeloid leukemia (AML) according to data to be presented at the EORTC-AACR-NCI Molecular Targets and Cancer Therapeutics Symposium in Barcelona

November 18, 2014

Can you reduce Graft versus Host Disease GvHD by regulating gut bacteria?

At the SITC 2014 annual meeting, Dr van den Brink presented data on how the bacteria in our gut (the intestinal microbiome) can impact GvHD.

November 18, 2014

Challenge of Cytokine Release Syndrome in CD19 CAR-T Cell Therapy

At the Society for Immunotherapy of Cancer (SITC) meeting last week, one of the Hot Topic sessions that took place after the conference formally ended was in managing the toxicities associated with chimeric antigen receptor T cell (CAR-T) therapy.

November 17, 2014