JCAR015 is dead. Long live JCAR015
Hans Bishop, Juno
After a rocky 2016 for Juno with JCAR015 and the trial that imploded unexpectedly and badly, the CEO Hans Bishop quietly announced that announced that ROCKET has been abandoned:
“2016 was a year of progress and learning for Juno and the cancer immunotherapy field. We continue to experience encouraging signs of clinical benefit in our trial addressing NHL, but we also recognize the unfortunate and unexpected toxicity we saw in our trial addressing ALL with JCAR015. We have decided not to move forward with the ROCKET trial or JCAR015 at this time.”
A strange year of hubris attracting nemesis might be another way of describing the events for some observers.
We covered the Juno roller coaster and events in July and December 2016 for those who want to catch up on the full history of this unfortunate and ongoing debacle:
- Juno setback by patient deaths due to CAR T cell neurotoxicity
- Juno plays Russian roulette with JCAR015
Where does the latest Juno news leave things and what can we expect going forward?
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