Without a doubt, there are multiple potential ways we can go about improving responses to cancer immunotherapy, not just in terms of targets, combination approaches, different modalities etc, but also by manipulating the tumour microenvironment or thinking about directing different immune cells in positive ways.
In our latest review, we look at one area where emerging work appears to bearing fruit as multiple groups suddenly get one of those, a-ha! moments.
It’s not just happening in one tumour type either, nor is it limited to one type of therapy or modality, which makes it all the more intriguing to think about.
We heard about one example of this mechanism last year and now it’s time to explore things in more detail. This also means companies quick on the uptake could well take advantage ahead of their competitors.