Can a monoDAC hit the groove against IMiDs and CELMoDs?
The groovy C4T Office
As we continue our in-depth post AACR21 coverage, it’s time for part two in the protein degradation series with a look at C4 Therapeutics and what we can learn from their preclinical data presentation of CFT7455, where they aim to selectively destroy disease-causing proteins in multiple myeloma and lymphomas through degradation of IKZF1/3.
Also included is the second half of an interview with their charismatic CSO, Dr Stew Fisher where we discuss degraders, glues, IMiDs and CELMoDs…
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