Ever Decreasing Circles
Fall Colors in Boston
The Fall cancer conference season is in full swing with the TARGETS and ESMO23 meetings both coming up this month.
Here we take a look at what to watch out for in both small and ‘large’ small molecules these include various epigenetic targets, KRAS, and SHP2.
The headline for today’s post was inspired by a British TV sitcom from the 1980s, which kind of reminds me of how perception of many of these targets has changed over time… as in time went on, in ever decreasing circles, the hype wore off and despair sets in.
Of course, there’s always redemption down the road in some form or other, as illustrated by the Fall and Rise of Reginald Perrin.
In this case, as the lustre fades on some of the frontrunners there’s now a rising tide of different – yet related – targets, as well as new compounds and combinations coming through – what’s not to like?
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