Same Controller, Opposite Outcomes
In this latest post from the American Society of Hematology meeting we explore some of the scientific data emerging from San Diego.
Specifically, we are looking at how transcription factors such as TOX2 can drive divergent fates in T and NK cells.
It might be tempting to think it sounds a bit dry, yet the findings could have important implications for future therapeutic developments – especially in the design of novel chimeric antigen receptor (CAR) cell therapies, an area where CAR-NK cells have constantly struggled with poor persistence.
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