Rotterdam, Feb 2023

With so much focus on T cell fitness and exhaustion of late I wanted to highlight an area in the CAR-T cell space, which was all the rage a decade ago then quietly fizzled somewhat, leading many observers to wonder if it was great in theory, but not so much in practice.

This subniche is going through a renaissance of sorts as more research is conducted and we learn enough from the experiments and past mistakes to start moving forward again.

In this post, we’re gimng to focus exclusively on one of these aspects and see what’s new and where things might be headed because this isn’t an isolated incident…

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