What happens when an intractable target becomes druggable-ish
In the third of our Preview series from this year’s AACR meeting, we’re taking a look at an early, if rapidly evolving competitive landscape involving several different modalities – proving there’s often more than one way to skin a cat drug a particular target!
When we last covered this topic there were barely half a dozen developments to highlight, since then this niche has rapidly exploded with a variety of molecules and different companies to add to the mix.
Some key questions facing this field include how will we move on from dose escalation studies, what combinations will make sound sense, and which modalities might offer a wider therapeutic window in order to be combinable with other approaches? People will always have favourites, so we took an unbiased look at the state of play.
It’s never as easy as it first appears…
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