Combined checkpoint inhibition and chemotherapy – useful or not?
How do we help patients who are non-responders or have stable disease respond to checkpoint inhibitors? Will chemotherapy combos help or not?
June 8, 2015
Emerging new biomarker for predicting checkpoint inhibitor responders
Predictive biomarkers of response will be key to reimbursement of immunotherapies in Europe. One is potentially emerging for ipilimumab (Yervoy), which may be useful in speeding up access.
March 19, 2015
Next generation approaches to immuno-oncology – where next?
What's next in immuno-oncology: what are potential ways to tackle the patients who do not respond to checkpoint immunotherapy?
January 8, 2015
The Science of PD1 PDL1 Cancer Immunotherapy
The science of targeting PD-1 and it's ligand PD-L1 in cancer immunotherapy is highlighted in five Letters published in Nature this week.
November 26, 2014
Targeting CD40 in Cancer Immunotherapy
How can we jumpstart the immune system to enable more patients to respond? At SITC we learned more about targeting CD40 to achieve this.
November 20, 2014
Can you reduce Graft versus Host Disease GvHD by regulating gut bacteria?
At the SITC 2014 annual meeting, Dr van den Brink presented data on how the bacteria in our gut (the intestinal microbiome) can impact GvHD.
November 18, 2014
Challenge of Cytokine Release Syndrome in CD19 CAR-T Cell Therapy
At the Society for Immunotherapy of Cancer (SITC) meeting last week, one of the Hot Topic sessions that took place after the conference formally ended was in managing the toxicities associated with chimeric antigen receptor T cell (CAR-T) therapy.
November 17, 2014
Will combining anti-OX40 with a checkpoint inhibitor matter in cancer?
OX40 could be an exciting new target in immune-oncology that could be combined with checkpoint inhibitors to improve the T cell response.
November 11, 2014
SITC 2014 Cancer Immunotherapy Day 1
Reflections on Day 1 of the 2014 annual meeting of the Society for Immunotherapy of Cancer (SITC).
November 8, 2014
SITC 2014 Cancer Immunotherapy Workshop Review
Day 1 of the SITC annual meeting started with two workshops on immunotherapy and combination therapy
November 7, 2014
SITC 2014 Cancer Immunotherapy Annual Meeting Preview
This week sees the start of the 2014 annual meeting of the Society for Immunotherapy of Cancer (SITC) at National Harbor, MD. We’re excited to be attending this meeting for the first time.
November 4, 2014