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Beyond the Topo-I Rush: Finding Space in a Crowded ADC Landscape

When the future of ADCs and bispecifics collide

November 11, 2024
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ESMO24 Preview 5 – Late Breaking standouts

What can we learn from the initial LBA abstract titles?

August 22, 2024
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We may never know

Why what we don't know might kill a few cancer programs

August 19, 2024
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Postcards on early oncology drug development

A look atfive recent developments and what we can learn from them

July 11, 2024
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On biomarkers and bispecifics

When the going gets tough, the tough get going...

March 28, 2024
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Exploring novel targets and modalities in advanced cancer

Where we look at half a dozen emerging agents and put them through their paces

February 6, 2024
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Shining a beacon

Our take on data from half a dozen key trials at ASCO GI24

January 24, 2024
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Key oncology take aways and insights from Days 1 and 2 at JPM24

Winners and losers at JPM24

January 10, 2024
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You can’t put the genie back in the bottle

Important lessons learned from failure

December 8, 2023
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Setting the scene

Spotting the winners and losers in the gastric cancer niche

November 8, 2023
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Ever Decreasing Circles

From epigenetics to SHP2, a look at various upcoming presentations this month

October 5, 2023
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Gunning for new targets, new approaches

From CAR-T cells to protein degradation

September 19, 2023
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Exploring unexpected targets in brain tumours

As we head into the long August Bank Holiday and Labor Day celebrations, I wanted to offer some…

August 24, 2023
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What’s hot in lung cancer?

Preview - Wwat to watch for at WCLC23

July 27, 2023
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Making sense of all the TIGIT data at ASCO23

Continuing our coverage of the annual meeting of ASCO in Chicago I felt compelled to review the actual…

June 6, 2023
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On TIGIT, ADCs, and other stories

Some ASCO23 abstracts to watch out for and why

May 31, 2023
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Tipping the TIGIT balance

How can we overcome immune escape in relation to TIGIT therapies?

January 9, 2023
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Chasing the alpha

A deeper look at the ARC-7 TIGIT readout

December 20, 2022
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Emerging biotechs and novel IO concepts to watch out for

10 early stage IO biotechs to watch out for

November 30, 2022
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SITC Preview 2 – a look at novel and emerging IO targets

Five areas of early stage IO developments to watch out for

October 14, 2022
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The spectre of MetMAB rises again!

Six important factors to consider when looking at the SKYSCRAPER-01 TIGIT readout

May 11, 2022
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The paradox of immune cell populations and transcription factors

Can you have your immune cake and eat it?

March 23, 2022
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Science drives innovation

A careful look at the latest anti-TIGIT data

January 25, 2022
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What to watch out for on the CAR-T cell therapy front

Several controversies abound in the CAR-T cell niche this year, plus what's coming next?

December 7, 2021
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Lessons learned from SITC – Part 1

Sometimes we learn more from failure than we do from success

November 16, 2021
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Scores on the doors in the TIGIT niche

Update on the various runners and riders in the TIGIT niche

November 3, 2021
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Washington DC in Fall

SITC21 – What to Watch out for

SITC 2021 Preview

October 22, 2021
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Looking east at a now familiar horizon

A careful look at what we can learn from the Beigene anti-TIGIT data for ociperlimab

July 6, 2021
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Tackling immunosuppression with a dual approach to TIGIT and adenosine

Do we need to target the adenosine fog as well as TIGIT in NSCLC?

June 24, 2021
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A twist in the IO tail

Going beyond the obvious conclusion with anti-LAG3 therapy

May 19, 2021
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Emerging developments and trends in advanced lung cancer

Gems from the WCLC20 poster hall which may make an impact

February 9, 2021
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Parallel lines: opportunities and challenges in GI cancers

Important developments on the GI cancer front to watch out for

January 19, 2021
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A contrarian view of key cancer trial results

Winners, losers and risers... who goes where in the final analysis?

October 8, 2020
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Hubble Space Telescope, Spitzer Space Telescope

On black holes and rising supernova stars in oncology

Rising stars become supernovas or disappear into a black hole of R&D - a look at what we can learn from one company's early stage compounds

October 6, 2020
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Can we add fire to the immune system with TIGIT?

A look at Genentech's tiragolumab (anti-TIGIT) in advanced lung cancer

June 1, 2020
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Putting some colour on the TIGIT niche

A look at what a young up and coming biotech in the TIGIT space are doing and how they see their approach being differentiated from the competition.

May 12, 2020
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Every cloud has a silver lining

What to watch out for at AACR20 - the first of our meeting previews is here!

April 15, 2020
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10 early phase ASH19 abstracts with a difference

A look at off Broadway abstracts on early new product development and scientific findings of interest

November 26, 2019
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Next generation approaches to immuno-oncology – where next?

What's next in immuno-oncology: what are potential ways to tackle the patients who do not respond to checkpoint immunotherapy?

January 8, 2015